The results are presented of an experimental activity performed in the RFX-mod device aimed at characterizing plasma dynamics in the so-called Ultralow-q (ULq) magnetic configuration, which corresponds to edge safety factor values below 1. The role of the edge safety factor in determining plasma dynamics is studied. In particular, a characterization of MHD activity is performed. The results of dedicated non-linear 3D visco-resistive MHD simulations are in good quantitative agreement with the experimental observations. In particular, the predicted tendency for ULq plasmas to be characterized by magnetic spectra dominated by a single mode (either a kink or a double resonant internal mode) is confirmed by experiment. Magnetic reconnection plays a relevant role in determining the dynamics of the magnetic topology. Both almost quiescent and largely fluctuating plasmas are observed with a strong sensitivity on the edge safety factor. The main MHD properties of the ULq are compared to those of RFP and tokamak discharges, also produced in the RFX-mod device. MHD modes exhibit toroidal rotation at a frequency depending on mode amplitude. Differently from what encountered in RFP plasmas at comparable current levels, no wall locking is detected.