Hydrodynamics and robustness of three high yield targets within the HiPER project are presented. Using realistic illumination nonuniformity configuration, hydrodynamic perturbations sensitivity analysis is carried out. A rather simple hydrodynamic perturbation modeling sequence is validated thanks to 2D simulations. 1D simulations post-processed with such a modeling sequence provide a good estimation of the thermonuclear burn. First estimates of hydrodynamic safety factor are given.