The problem of producing fusion power with low neutron emission has been debated in the past in the framework of the magnetic confinement fusion research. Proposals are still being renewed to use advanced fuels in various plasma systems. Since today's toroidal devices cannot support plasma conditions suitable for a large fusion production with such fuels, new concepts and configurations have been studied, where the plasma components are not in a thermal equilibrium. Here, a system of a neutral beam injected into a confined plasma is considered where fusion is produced only between the beam and plasma ions. The collisional slowing down of the beam into the plasma is described by a fluid model. General considerations in this model allow conditions to be found for the fusion-produced power to breakeven against the power needed to sustain the system itself. These conditions are only necessary since the nuclear power is maximized in the present analysis by using favourable assumptions. Nevertheless, the results for different advanced fuels indicate again the very high difficulty of getting a net power produced by the fusion of such fuels, unless the plasma target temperature reaches very high and unrealistic values.