It is shown that interchange type plasma instabilities can be stabilized by inverted flow velocity profiles. The stabilization criterion is that the gradient in flow velocity be opposite to that of the plasma density and the velocity gradient scale length be sufficiently smaller than that of the density. This technique is applied to ballooning modes and curvature driven trapped particle instabilities in tokamaks. The necessary inversion of the toroidal flow velocity profile can he achieved by appropriate injection of neutral beams