The paper presents theoretical analysis and experimental results concerning the major physical issues in the shock-ignition approach. These are the following: generation of a high amplitude shock in the imploding target, laser–plasma interaction physics under the conditions of high laser intensities needed for high amplitude shock excitation, symmetry and stability of the shock propagation, role of fast electrons in the symmetrization of the shock pressure and the fuel preheat. The theoretical models and numerical simulations are compared with the results of specially designed experiments on laser plasma interaction and shock excitation in plane and spherical geometries.