The transport behavior of hydrogen isotopes through tungsten (W) is a critical factor for the safety and economics of fusion reactors. This study investigates the impact of intense helium (He) plasma irradiation on the deuterium (D) transport characteristics in W. High-flux He plasma irradiation was utilized to induce a nanoscale fuzz structure on the W surface. The effects of this structure on the permeation and retention of D were subsequently examined using plasma-driven permeation (PDP) and thermal desorption spectroscopy (TDS). The TDS results reveal that the presence of fuzz significantly enhances D retention due to an increased density of trapping sites introduced by surface nanostructure and He bubble formation. In contrast, PDP results indicate only a slight reduction in the steady-state permeation flux. Moreover, comparative analysis between the first and second PDP cycles demonstrates a more substantial increase in the apparent diffusion coefficient for fuzz samples, indicating the formation of a higher density of irreversible traps. These findings suggest that while the fuzz structure acts as an effective near-surface reservoir for hydrogen isotopes, it has limited influence on long-term permeation behavior, which remains governed by bulk diffusion and reversible trapping mechanisms.