The suggestion that the surface of the moon may be mined for 3He to be used as a fuel in terrestrial fusion reactors has recently been made. A fusion reactor based on the D—3He reaction would have the advantage that most of the power produced would be in the form of charged non-radioactive particles. However, secondary D—D and D—T reactions also occur. A study is made of the consequences of the radioactivity induced by the neutrons from these reactions with respect to waste disposal. A generic first wall and shield 0.4 m thick consisting of 7% structure, 73% H2O and 20% void was used as a test case. The structural materials considered were two austenitic stainless steels (PCA and Tenelon), two ferritic alloys (HT-9 and a low activity modification of HT-9), and a vanadium alloy (V15Cr5Ti). The results of the calculations show that for operation at a fusion power loading of 1 MW/m2 for a thirty year reactor lifetime, Tenelon, the low activity HT-9 and the vanadium alloy meet surface waste disposal requirements consistent with those published in the U.S. Code of Federal Regulations (10CRF61). If five percent boron is added to the water to suppress (n, γ) reactions, HT-9 and PCA structures are acceptable. Calculations of a first wall and shield designed for a 600 MW reactor D—3He operating at a fusion power loading of 2.94 MW/m2 indicate that Tenelon may be used as structure and meet waste disposal requirements after thirty years of operation. It is concluded that the use of a D—3He cycle allows surface burial of activated reactor components and results in a significant reduction in the volume of waste.