A detailed comparison between the observed and expected loss of alpha-like MeV fusion products in TFTR is presented. The D-D fusion products (mainly the 1 MeV triton) were measured with a 2-D imaging scintillation detector. The expected first-orbit loss was calculated with a simple Lorentz orbit code. In almost all cases the measured loss was consistent with the expected first-orbit loss model. Exceptions are noted for small major radius plasmas and during strong MHD activity.