The diagnostics slim cassette (DSC) is a concept currently proposed for DEMO to host the microwave reflectometry diagnostic in a dedicated poloidal section, for the feedback control of plasma position and shape, also providing the radial edge density profile at several poloidal angles. This DSC, which is expected to house up to 100 antennas and waveguides, is to be integrated with the breeding blanket (BB) segments. Moreover, it is being designed with remote handling compatibility in mind to facilitate a 'fast' exchange by remote maintenance (RM) when needed, fulfiling one of the aims of the work package diagnostic and control. In this approach the pre-assembled (banana-shaped) DSC modules are inserted/removed from the upper port (UP) of the vacuum vessel (VV), at least when the BB segments are replaced. Here the main constraints related to the integration of the DSC with the BB, the UP and the equatorial port are identified and discussed in detail, with a strong focus on the required RM operations inside the VV (in-vessel), providing solutions that can be adapted to present and future blanket and UP designs.