The experimental feasibility of the laser-driven ion acceleration concept with multi-layered, foam-based targets has been investigated. Targets with the required features have been produced and characterized, exploiting the potential of the pulsed laser deposition technique. In the intensity range 1016–1017 W cm−2, they allow us to obtain maximum proton energies 2–3 times higher compared to bare solid targets, able to reach and surpass the MeV range with both low and ultrahigh contrast pulses. The results of two-dimensional particle-in-cell simulations, supporting the interpretation of the experimental results, and directions to exploit the concept also at ultrahigh intensities, are presented.