A simple model for the interaction between a solid microsphere and a surrounding dense and hot plasma shows that plasma columns such as those produced in plasma focus devices may drive the implosion of the microsphere, thus creating situations of interest for inertial confinement research. The method can be used for microspheres structured in such a way that the implosion does not require a critical temporal profile of the pressure pulse applied on the surface, i.e. for microspheres having thin shells. In this case, it is shown that the plasma column of a plasma focus fed by a condenser bank of a few hundred kilojoules is, potentially, a driver comparable to a multibeam kilojoule Nd laser facility. It is concluded that attention should be paid to plasma focus research in the context of inertial confinement.