Atmospheric non-thermal plasma (NTP) has been recognized as an important tool for the abatement of pollutants and for promoting various chemical reactions in gas or in liquid. Indoor air cleaners have been mass-produced and proved to be effective for the removal of odour and allergen. NTP has various potential applications in environmental remediation, such as the removal of volatile organic pollutants, simultaneous removal of NOx and soot in diesel exhaust and sterilization of air and water. To improve the efficiency of plasma chemical processes, a combination of NTP and catalysts/absorbents is effective. Synergetic effects have been recognized; however, its mechanism remains subject to further investigations. The generation of non-thermal discharge plasma and several industrial applications are presented in this paper.