In order for ITER to be capable of operating in advanced tokamak operating regimes, characterized by a high fusion gain, good plasma confinement, magnetohydrodynamic stability and a non-inductively driven plasma current, for extended periods of time, several challenging plasma control problems still need to be solved. Setting up a suitable toroidal current density profile in the tokamak is key for one possible advanced operating scenario characterized by non-inductive sustainment of the plasma current. At the DIII-D tokamak, the goal is to create the desired current profile during the ramp-up and early flat-top phases of the plasma discharge and then actively maintain this target profile for the remainder of the discharge. The evolution in time of the toroidal current profile in tokamaks is related to the evolution of the poloidal magnetic flux profile, which is modelled in normalized cylindrical coordinates using a first-principles, nonlinear, dynamic partial differential equation (PDE) referred to as the magnetic diffusion equation. The magnetic diffusion equation is combined with empirical correlations developed from physical observations and experimental data from DIII-D for the electron temperature, the plasma resistivity and the non-inductive current drive to develop a simplified, control-oriented, nonlinear, dynamic PDE model of the poloidal flux profile evolution valid for low confinement mode discharges. In this work, we synthesize a robust feedback controller to reject disturbances and track a desired reference trajectory of the poloidal magnetic flux gradient profile by employing the control-oriented model of the system. A singular value decomposition of the static gain matrix of the plant model is utilized to identify the most relevant control channels and is combined with the dynamic response of system around a given operating trajectory to design the feedback controller. A general framework for real-time feedforward + feedback control of magnetic and kinetic plasma profiles was implemented in the DIII-D Plasma Control System and was used to demonstrate the ability of the feedback controller to control the toroidal current profile evolution in the DIII-D tokamak. These experiments constitute the first time ever a first-principles-driven, model-based, closed-loop magnetic profile controller was successfully implemented and tested in a tokamak device.