The basic problem of particle end-loss in a magnetic mirror field with an electrostatic confining potential is considered. The analytic treatments of Pastukhov and Chernin and Rosenbluth have been generalized to apply to any electrostatically confined species in a multi-species plasma, and the Pastukhov analysis has been extended to apply to arbitrary magnetic-field profiles (instead of square-well). The analytic results are compared with results obtained from one-and two-dimensional Fokker-Planck codes. In particular the scaling with potential, mirror ratio, and effective charge is considered. The closest agreement (within 20%) is between the 2-D Fokker-Planck and generalized Pastukhov results.