AbstractThe requirements of the tritium plant for ITER have been persistently detailed in the last decade and have led to increasing demands, especially for the Tokamak Exhaust Processing (TEP). Efficient multistage processes have been designed and commissioned to demonstrate the very high detritiation factors required. The operation of components installed at the Tritium Laboratory Karlsruhe, e.g. of a permeator run under the conditions expected for the front-end section of TEP (first stage), the development of catalysts for use in a Permcat (final (third) stage) which is a combination of a counter-current flow permeator and a catalyst to promote the exchange between tritium containing molecules and protium in the gas phase as well as results from decontamination of the methane cracker, key component of the second stage, after failure of both the main and redundant heater are described.